MAIN RECENT PUBLICATIONS
2022
Bissonnette J*, Riescher-Tuczkiewicz A*, Gigante E, Bourdin C, Boudaoud L, Soliman H, Durand F, Ronot M, Valla D, Vilgrain V, de Raucourt E, Rautou PE
Predicting bleeding after liver biopsy using comprehensive clinical and laboratory investigations: A prospective analysis of 302 procedures
JTH. 2022
Al-Rifai R, Marie Vandestienne M, Lavillegrand JR, Mirault T, Cornebise J, Poisson J, Laurans L, Esposito B, James C, Mansier O, Hirsch P, Favale F, Braik R, Knosp C, Vilar J, Rizzo G, Zernecke A, Saliba A, Tedgui A, Lacroix M, Arrive L, Mallat Z, Taleb S, Diedisheim M, Cochain C, Rautou PE & Ait-Oufella H
JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm
Nature Communications. 2022
Artru F, Vietti-Violi N, Sempoux C, Barbosa JV , Becce F, Sah N, Marot A, Deltenre P, Moschouri E, Fraga M, Hocquelet A, Duran R, Moradpour D, Rautou PE*, Denys A*.
Portal vein recanalisation alone to treat severe portal hypertension in non-cirrhotic patients with chronic extrahepatic portal vein obstruction
JHEP Rep. 2022
Ram Valainathan S, Sartoris R, Elkrief L, Magaz M, Betancourt F, Pellegrino S, Nivolli A, Dioguardi Burgio M, Flattet Y, Terraz S, Drilhon N, Lazareth M, Herrou J, Bruno O, Payance A, Plessier A, Durand F, Ronot M, Valla D-C, Paradis V, Garcia-Pagan JC, Valérie Vilgrain V, Rautou PE.
Contrast-enhanced CT and liver surface nodularity for the diagnosis of porto-sinusoidal vascular disorder : a case-control study.
Hepatology 2022
De Broucker C, Plessier A , Ollivier-Hourmand I, Dharancy S, Bureau C, Cervoni JP, Sogni P, Goria O, Corcos O, Sartoris R, Ronot M, Vilgrain V , De Raucourt E , Zekrini K , Davy H, Durand F , Payancé A, Fidouh-Houhou N , Yazdanpanah Y, Valla D, Rautou PE .
Multicenter study on recent portal venous system thrombosis associated with cytomegalovirus disease
J Hepatol 2022
2021
Kostallari E, Valainathan S, Biquard L, Shah VH, Rautou PE .
Role of extracellular vesicles in liver diseases and their therapeutic potential
Adv Drug Deliv Rev 2021 Aug
Elkrief L, Lazareth M, Chevret S, Paradis V, Magaz M, Blaise L, Rubbia-Brandt L, Moga L, Durand F, Payancé A, Plessier A, Chaffaut C, Valla D, Malphettes M, Diaz A, Nault JC, Nahon P, Audureau E, Ratziu V, Castera L, Garcia Pagan JC, Ganne-Carrie N, Rautou PE .
Liver stiffness by transient elastography to detect porto-sinusoidal vascular liver disease with potal hypertension
Hepatology 2021 Jul
2020
Hammoutene A, Pierre-Emmanuel Rautou PE.
Role of autophagy in liver sinusoidal endothelial cells in nonalcoholic steatohepatitis
Med Sci (Paris) 2020 Aug-Sep
Thietart S , Pierre-Emmanuel Rautou PE.
Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view.
J Hepatol 2020 Jul
Biquard L , Valla D. , Rautou PE .
No evidence for an increased liver uptake of SARS-CoV-2 in metabolic-associated fatty liver disease.
J Hepatol 2020 May
Poisson J, Tanguy M, Davy H, Camara F, El Mdawar MB1, Kheloufi M, Dagher T, Devue C, Lasselin J, Plessier A, Merchant S, Blanc-Brude O, Souyri M, Mougenot N, Dingli F, Loew D, Hatem SN, James C, Villejal JL, Boulanger CM, Rautou PE.
Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm.
J Clin Invest 2020 Feb
Hammoutene A, Biquard L, Lasselin J, Kheloufi M, Tanguy M, Vion AC, Mérian J, Colnot N, Loyer X, Tedgui A, Codogno P, Lotersztajn S, Paradis V, Boulanger CM, Rautou PE.
A defect in endothelial autophagy occurs in patients with nonalcoholic steatohepatitis and promotes inflammation and fibrosis.
J Hepatol 2020 Mar.
2019
Elkrief L, Ferrusquia-Acosta J, Payancé A, Moga L, Tellez L, Praktiknjo M, Procopet B, Farcau O, De Lédinghen V, Yuldashev R, Tabchouri N, Barbier L, Dumortier J, Menahem B, Magaz M, Hernández-Gea V, Albillos A, Trebicka J, Spahr L, De Gottardi A, Plessier A, Valla D, Rubbia-Brandt L, Toso C1, Bureau C, Garcia-Pagan JC, Rautou PE; for VALDIG, an EASL consortium.
Abdominal Surgery in Patients With Idiopathic Noncirrhotic Portal Hypertension: A Multicenter Retrospective Study.
Hepatology. 2019 Sep.
Hammoutene A, Rautou PE.
Role of liver sinusoidal endothelial cells in non-alcoholic fatty liver disease.
J Hepatol. 2019 Jun.
Allaire M, Rautou PE, Codogno P, Lotersztajn S.
Autophagy in liver diseases: Time for translation?
J Hepatol. 2019 May.
Lejealle C, Paradis V, Bruno O, de Raucourt E, Francoz C, Soubrane O, Lebrec D, Bedossa P, Valla D, Mal H, Vilgrain V, Durand F, Rautou PE.
Evidence for an Association Between Intrahepatic Vascular Changes and the Development of Hepatopulmonary Syndrome.
Chest. 2019 Jan.
2018
Andrade F, Shukla A, Bureau C, Senzolo M, D’Alteroche L, Heurgué A, Garcia-Pagan JC, Turon F, Oberti F, Tripathi D, Roux O, Ceccaldi PF, de Raucourt E, Payancé A, Valla D, Plessier A, Rautou PE; VALDIG investigators.
Pregnancy in idiopathic non-cirrhotic portal hypertension: A multicentric study on maternal and fetal management and outcome.
J Hepatol. 2018 Aug 21.
Rautou PE, Busse J, Kheloufi M, Vion AC, Boulaftali Y, Stark K, Boulanger CM.
Endothelial Autophagy Does Not Influence Venous Thrombosis in Mice.
Thromb Haemost. 2018 Jun.
Poisson J, Hilscher MB, Tanguy M, Hammoutene A, Boulanger CM, Villeval JL, Simonetto DA, Valla D, Shah VH, Rautou PE.
Endothelial JAK2V617F does not enhance liver lesions in mice with Budd-Chiari syndrome.
J Hepatol. 2018 May.
Payancé A, Silva-Junior G, Bissonnette J, Tanguy M, Pasquet B, Levi C, Roux O, Nekachtali O, Baiges A, Hernández-Gea V, Laouénan C, Lebrec D, Albuquerque M, Paradis V, Moreau R, Valla D, Durand F, Boulanger CM, Garcia-Pagan JC, Rautou PE.
Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis.
Hepatology. 2018 Mar 30
2017
Vion AC*, Kheloufi M*, Hammoutene A, Poisson J, Lasselin J, Devue C, Pic I, Dupont N, Busse J, Starke K, Lafaurie-Janvore J, Barakatf AI, Loyer X, Souyri M, Viollet B, Julia P, Tedgui A, Codogno P, Boulanger CM*, Rautou PE*.
Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow.
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8675-E8684
Poisson J, Plessier A, Kiladjian JJ, Turon F, Cassinat B, Andreoli A, De Raucourt E, Goria O, Zekrini K, Bureau C, Lorre F, Cervantes F, Colomer D, Durand F, Garcia-Pagan JC, Casadevall N, Valla DC, Rautou PE*, Marzac C*;
French national network for vascular liver diseases. Selective testing for calreticulin gene mutations in patients with splanchnic vein thrombosis: A prospective cohort study.
J Hepatol. 2017 Sep;67(3):501-507
Bissonnette J, Altamirano J, Devue C, Roux O, Payance A, Lebrec D, Bedossa P, Valla D, Durand F, Ait-Oufella H, Sancho-Bru P, Caballeria J, Boulanger CM, Bataller R, Rautou PE.
A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.
Hepatology. 2017 Aug;66(2):555-563
Weiss E*, Rautou PE*, Fasseu M*, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.
Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.
J Hepatol. 2017 May
Poisson J, Lemoinne S, Boulanger C, Durand F, Moreau R, Valla D, Rautou PE.
Liver sinusoidal endothelial cells: physiology and role in liver diseases.
J Hepatol. 2017 Jan;66(1):212-227.
2016
Rautou PE, Tatsumi K, Antoniak S, Owens AP 3rd, Sparkenbaugh E, Holle LA, Wolberg AS, Kopec AK, Pawlinski R, Luyendyk JP, Mackman N.
Hepatocyte Tissue Factor Contributes to the Hypercoagulable State in a Mouse Model of Chronic Liver Injury.
J Hepatol. 2016 Jan;64(1):53-9.
Loyer X, Paradis V, Hénique C, Vion AC, Colnot N, Guerin CL, Devue C, On S, Scetbun J, Romain M, Paul JL, Rothenberg ME, Marcellin P, Durand F, Bedossa P, Prip-Buus C, Baugé E, Staels B, Boulanger CM, Tedgui A, Rautou PE.
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.
Gut. 2016 Nov;65(11):1882-1894.
2014
Lemoinne S, Thabut D, Housset C, Moreau R, Valla D, Boulanger CM, Rautou PE.
The emerging roles of microvesicles in liver diseases.
Nat Rev Gastro Hepat. 2014 Jun;11(6):350-61
2012
Rautou PE, Bresson J, Sainte-Marie Y, Vion AC, Paradis V, Renard JM, Devue C, Heymes C, Letteron P, Elkrief L, Lebrec D, Valla D, Tedgui A, Moreau R, Boulanger CM.
Abnormal Plasma Microparticles Impair Vasoconstrictor Responses in Patients with Cirrhosis.
Gastroenterology. 2012 Jul;143(1):166-76.
Bissonnette J*, Riescher-Tuczkiewicz A*, Gigante E, Bourdin C, Boudaoud L, Soliman H, Durand F, Ronot M, Valla D, Vilgrain V, de Raucourt E, Rautou PE
Predicting bleeding after liver biopsy using comprehensive clinical and laboratory investigations: A prospective analysis of 302 procedures
JTH. 2022
Al-Rifai R, Marie Vandestienne M, Lavillegrand JR, Mirault T, Cornebise J, Poisson J, Laurans L, Esposito B, James C, Mansier O, Hirsch P, Favale F, Braik R, Knosp C, Vilar J, Rizzo G, Zernecke A, Saliba A, Tedgui A, Lacroix M, Arrive L, Mallat Z, Taleb S, Diedisheim M, Cochain C, Rautou PE & Ait-Oufella H
JAK2V617F mutation drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm
Nature Communications. 2022
Artru F, Vietti-Violi N, Sempoux C, Barbosa JV , Becce F, Sah N, Marot A, Deltenre P, Moschouri E, Fraga M, Hocquelet A, Duran R, Moradpour D, Rautou PE*, Denys A*.
Portal vein recanalisation alone to treat severe portal hypertension in non-cirrhotic patients with chronic extrahepatic portal vein obstruction
JHEP Rep. 2022
Ram Valainathan S, Sartoris R, Elkrief L, Magaz M, Betancourt F, Pellegrino S, Nivolli A, Dioguardi Burgio M, Flattet Y, Terraz S, Drilhon N, Lazareth M, Herrou J, Bruno O, Payance A, Plessier A, Durand F, Ronot M, Valla D-C, Paradis V, Garcia-Pagan JC, Valérie Vilgrain V, Rautou PE.
Contrast-enhanced CT and liver surface nodularity for the diagnosis of porto-sinusoidal vascular disorder : a case-control study.
Hepatology 2022
De Broucker C, Plessier A , Ollivier-Hourmand I, Dharancy S, Bureau C, Cervoni JP, Sogni P, Goria O, Corcos O, Sartoris R, Ronot M, Vilgrain V , De Raucourt E , Zekrini K , Davy H, Durand F , Payancé A, Fidouh-Houhou N , Yazdanpanah Y, Valla D, Rautou PE .
Multicenter study on recent portal venous system thrombosis associated with cytomegalovirus disease
J Hepatol 2022
2021
Kostallari E, Valainathan S, Biquard L, Shah VH, Rautou PE .
Role of extracellular vesicles in liver diseases and their therapeutic potential
Adv Drug Deliv Rev 2021 Aug
Elkrief L, Lazareth M, Chevret S, Paradis V, Magaz M, Blaise L, Rubbia-Brandt L, Moga L, Durand F, Payancé A, Plessier A, Chaffaut C, Valla D, Malphettes M, Diaz A, Nault JC, Nahon P, Audureau E, Ratziu V, Castera L, Garcia Pagan JC, Ganne-Carrie N, Rautou PE .
Liver stiffness by transient elastography to detect porto-sinusoidal vascular liver disease with potal hypertension
Hepatology 2021 Jul
2020
Hammoutene A, Pierre-Emmanuel Rautou PE.
Role of autophagy in liver sinusoidal endothelial cells in nonalcoholic steatohepatitis
Med Sci (Paris) 2020 Aug-Sep
Thietart S , Pierre-Emmanuel Rautou PE.
Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view.
J Hepatol 2020 Jul
Biquard L , Valla D. , Rautou PE .
No evidence for an increased liver uptake of SARS-CoV-2 in metabolic-associated fatty liver disease.
J Hepatol 2020 May
Poisson J, Tanguy M, Davy H, Camara F, El Mdawar MB1, Kheloufi M, Dagher T, Devue C, Lasselin J, Plessier A, Merchant S, Blanc-Brude O, Souyri M, Mougenot N, Dingli F, Loew D, Hatem SN, James C, Villejal JL, Boulanger CM, Rautou PE.
Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm.
J Clin Invest 2020 Feb
Hammoutene A, Biquard L, Lasselin J, Kheloufi M, Tanguy M, Vion AC, Mérian J, Colnot N, Loyer X, Tedgui A, Codogno P, Lotersztajn S, Paradis V, Boulanger CM, Rautou PE.
A defect in endothelial autophagy occurs in patients with nonalcoholic steatohepatitis and promotes inflammation and fibrosis.
J Hepatol 2020 Mar.
2019
Elkrief L, Ferrusquia-Acosta J, Payancé A, Moga L, Tellez L, Praktiknjo M, Procopet B, Farcau O, De Lédinghen V, Yuldashev R, Tabchouri N, Barbier L, Dumortier J, Menahem B, Magaz M, Hernández-Gea V, Albillos A, Trebicka J, Spahr L, De Gottardi A, Plessier A, Valla D, Rubbia-Brandt L, Toso C1, Bureau C, Garcia-Pagan JC, Rautou PE; for VALDIG, an EASL consortium.
Abdominal Surgery in Patients With Idiopathic Noncirrhotic Portal Hypertension: A Multicenter Retrospective Study.
Hepatology. 2019 Sep.
Hammoutene A, Rautou PE.
Role of liver sinusoidal endothelial cells in non-alcoholic fatty liver disease.
J Hepatol. 2019 Jun.
Allaire M, Rautou PE, Codogno P, Lotersztajn S.
Autophagy in liver diseases: Time for translation?
J Hepatol. 2019 May.
Lejealle C, Paradis V, Bruno O, de Raucourt E, Francoz C, Soubrane O, Lebrec D, Bedossa P, Valla D, Mal H, Vilgrain V, Durand F, Rautou PE.
Evidence for an Association Between Intrahepatic Vascular Changes and the Development of Hepatopulmonary Syndrome.
Chest. 2019 Jan.
2018
Andrade F, Shukla A, Bureau C, Senzolo M, D’Alteroche L, Heurgué A, Garcia-Pagan JC, Turon F, Oberti F, Tripathi D, Roux O, Ceccaldi PF, de Raucourt E, Payancé A, Valla D, Plessier A, Rautou PE; VALDIG investigators.
Pregnancy in idiopathic non-cirrhotic portal hypertension: A multicentric study on maternal and fetal management and outcome.
J Hepatol. 2018 Aug 21.
Rautou PE, Busse J, Kheloufi M, Vion AC, Boulaftali Y, Stark K, Boulanger CM.
Endothelial Autophagy Does Not Influence Venous Thrombosis in Mice.
Thromb Haemost. 2018 Jun.
Poisson J, Hilscher MB, Tanguy M, Hammoutene A, Boulanger CM, Villeval JL, Simonetto DA, Valla D, Shah VH, Rautou PE.
Endothelial JAK2V617F does not enhance liver lesions in mice with Budd-Chiari syndrome.
J Hepatol. 2018 May.
Payancé A, Silva-Junior G, Bissonnette J, Tanguy M, Pasquet B, Levi C, Roux O, Nekachtali O, Baiges A, Hernández-Gea V, Laouénan C, Lebrec D, Albuquerque M, Paradis V, Moreau R, Valla D, Durand F, Boulanger CM, Garcia-Pagan JC, Rautou PE.
Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis.
Hepatology. 2018 Mar 30
2017
Vion AC*, Kheloufi M*, Hammoutene A, Poisson J, Lasselin J, Devue C, Pic I, Dupont N, Busse J, Starke K, Lafaurie-Janvore J, Barakatf AI, Loyer X, Souyri M, Viollet B, Julia P, Tedgui A, Codogno P, Boulanger CM*, Rautou PE*.
Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow.
Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8675-E8684
Poisson J, Plessier A, Kiladjian JJ, Turon F, Cassinat B, Andreoli A, De Raucourt E, Goria O, Zekrini K, Bureau C, Lorre F, Cervantes F, Colomer D, Durand F, Garcia-Pagan JC, Casadevall N, Valla DC, Rautou PE*, Marzac C*;
French national network for vascular liver diseases. Selective testing for calreticulin gene mutations in patients with splanchnic vein thrombosis: A prospective cohort study.
J Hepatol. 2017 Sep;67(3):501-507
Bissonnette J, Altamirano J, Devue C, Roux O, Payance A, Lebrec D, Bedossa P, Valla D, Durand F, Ait-Oufella H, Sancho-Bru P, Caballeria J, Boulanger CM, Bataller R, Rautou PE.
A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis.
Hepatology. 2017 Aug;66(2):555-563
Weiss E*, Rautou PE*, Fasseu M*, Giabicani M, de Chambrun M, Wan J, Minsart C, Gustot T, Couvineau A, Maiwall R, Hurtado-Nedelec M, Pilard N, Lebrec D, Valla D, Durand F, de la Grange P, Monteiro RC, Paugam-Burtz C, Lotersztajn S, Moreau R.
Type I interferon signaling in systemic immune cells from patients with alcoholic cirrhosis and its association with outcome.
J Hepatol. 2017 May
Poisson J, Lemoinne S, Boulanger C, Durand F, Moreau R, Valla D, Rautou PE.
Liver sinusoidal endothelial cells: physiology and role in liver diseases.
J Hepatol. 2017 Jan;66(1):212-227.
2016
Rautou PE, Tatsumi K, Antoniak S, Owens AP 3rd, Sparkenbaugh E, Holle LA, Wolberg AS, Kopec AK, Pawlinski R, Luyendyk JP, Mackman N.
Hepatocyte Tissue Factor Contributes to the Hypercoagulable State in a Mouse Model of Chronic Liver Injury.
J Hepatol. 2016 Jan;64(1):53-9.
Loyer X, Paradis V, Hénique C, Vion AC, Colnot N, Guerin CL, Devue C, On S, Scetbun J, Romain M, Paul JL, Rothenberg ME, Marcellin P, Durand F, Bedossa P, Prip-Buus C, Baugé E, Staels B, Boulanger CM, Tedgui A, Rautou PE.
Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression.
Gut. 2016 Nov;65(11):1882-1894.
2014
Lemoinne S, Thabut D, Housset C, Moreau R, Valla D, Boulanger CM, Rautou PE.
The emerging roles of microvesicles in liver diseases.
Nat Rev Gastro Hepat. 2014 Jun;11(6):350-61
2012
Rautou PE, Bresson J, Sainte-Marie Y, Vion AC, Paradis V, Renard JM, Devue C, Heymes C, Letteron P, Elkrief L, Lebrec D, Valla D, Tedgui A, Moreau R, Boulanger CM.
Abnormal Plasma Microparticles Impair Vasoconstrictor Responses in Patients with Cirrhosis.
Gastroenterology. 2012 Jul;143(1):166-76.