EXTRACELLULAR VESICLES CORE FACILITY

​With its many years of experience, the extracellular vesicle core facility will assist you in discovering how extracellular vesicles can play a role in your field. We can offer for your projects:
Isolation or generation of vesicles
Detailed and extensive vesicle characterization
Identification and quantification in large patient cohorts

More information on extracellular vesicles
•Théry C. et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018). J Extracell vesicles. 2018;7:1535750
•Coumans F. et al. Methodological guidelines to study extracellular vesicles. Circ Res . 2017; 120:1632-48
•Ridger VC et al. Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. Thromb Haemost.2017;117:1296-1316

Some of our recent studies on extracellular vesicles
•Elkrief L. et al. Hepatocyte-derived biomarkers predict liver-related events at 2 years in Child-Pugh class A alcohol-related cirrhosis. Journal of Hepatology. 2023
•Payancé A. et al. Hepatocyte microvesicle levels improve prediction of mortality in patients with cirrhosis. Hepatology. 2018 Oct;68:1508-1518
•Bissonnette J et al. A prospective study of the utility of plasma biomarkers to diagnose alcoholic hepatitis. Hepatology. 2017;66:555-563
•Lemoinne S et al. The emerging roles of microvesicles in liver diseases. Nat Rev Gastroenterol Hepatol. 2014;11:350-61



Contact us
Pierre-Emmanuel Rautou
[email protected]
Marion Tanguy
[email protected]
Centre de recherche sur l’inflammation – UMR 1149
Faculté de médecine site Bichat
3e étage Porte 378
01 57 27 77 31

---